Genetic and environmental components of family history in type 2 diabetes
نویسندگان
چکیده
منابع مشابه
Increased risk of type 2 diabetes from a family history of coronary heart disease and type 2 diabetes.
T he “common soil” hypothesis (1) suggests that a family history of cardiovascular disease (CVD) increases the risk of type 2 diabetes through the common predispositions of obesity (2–7), hypertension (8), metabolic syndrome (9), and other pathways. While several studies (10–12) have shown that a family history of diabetes can increase cardiovascular risk, including subclinical atherosclerosis ...
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BACKGROUND Type 2 diabetes mellitus (T2DM) has a strong genetic component, and its prevalence is notably increased in the family members of T2DM patients. However, there are few studies about the family history of T2DM. We carried out this study to assess the influences of family history on clinical characteristics in T2DM patients. METHODS This is a cross-sectional study involving 651 T2DM p...
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ژورنال
عنوان ژورنال: Human Genetics
سال: 2014
ISSN: 0340-6717,1432-1203
DOI: 10.1007/s00439-014-1519-0